Author: Yili Hu Abstract: Purpose: To observe the clinical effect of Pingwei Granule Mixture for syndrome of dampness-heat of spleen and stomach of chronic non-atrophic gastritis. Methods: In open randomized controlled clinical trial, 180 cases of chronic non-atrophic gastritis with dampness-heat syndrome of spleen and stomach were divided into treatment group (120 cases) and control group (60 cases). The treatment group was treated with Pingwei Granule Mixture (92g) three ti

摘要 目的：观察平胃颗粒合剂对慢性非萎缩性胃炎中医脾胃湿热证病人的临床疗效。 方法：釆用开放性随机对照临床试验方法，将180例慢性非萎缩性胃炎中医脾胃湿热证患者分为治疗组120例，对照组60例。治疗组以平胃颗粒合剂共92克，分三次，每日饭前半小时开水冲服；对照组用奥美拉唑片20毫克，一日二次，饭后半小时口服，枸橼酸钾胶囊150毫克，一日三次，饭前半小时口服。四周为一疗程。结果：治疗组与对照组的临床总有效率分别为93.33%和73.33%（P＜0.05)；治疗组与对照组胃脘疼痛、脘腹痞胀、大便溏薄、纳呆少食、舌苔黄腻五大主症的有效率分别为：91.89%和75.93%、95.83%和71.67%、91.92%和72.72%、94.20%和72.97%、92.50%和73.33%（P＜0.01); 治疗组与对照组中各30例的胃镜总有效率为90.00%和66.67%(P＜0.05); 治疗组97例和对照组45例的幽门螺旋杆菌近期清除率为82.47%和51.11%(P＜0.01), 远期根除率为56.25%和27.27%（P＜0.05)。结论：平胃颗粒合剂